17-Dec-2024 Proposed Uniprot Canonical changes:

Canonical changes suggested 17-Dec-2024

Displayed dataset: pmam2025_01om102_mane_sp_sp_241217.tab raw data	Clade construction: panther version:17.0 UP version: 2024_03 (Ensembl 112) aln_min_taxa: 3 clade_min_taxa: 3

Alternate subsets pmam2025_01om102_mane_all_241217.tab raw data pmam2025_01om102_mane_sp_tr_241217.tab raw data pmam2025_01om102_mane_tr_tr_241217.tab raw data

Search options: Accession: Taxon: MANE status: PantherID: Reverse list

Number of changes (All ): 116
MANE_good: 38 MANE_bad: 77

Panther ID:

canon cost

prop. cost

n_tax

n_canon

rank_score

MANE

TAXON canon_acc

(len) –> prop_acc

(len)

PTHR45640:SF14

0.1168

0.0006

1238.95

MANE_good

MESAU

sp|P02497

(196)

–>

sp|P02497-2

(173)

PTHR46716:SF1

0.0442

0.0001

954.87

MANE_bad

HUMAN

sp|O43318

(606)

–>

sp|O43318-2

(579)

PTHR22826:SF117

0.2317

0.0072

939.92

MANE_bad

HUMAN	sp\|Q86VW2	(580)	–>	sp\|Q86VW2-3	(619)
HUMAN	sp\|Q58EX7	(1191)	–>	sp\|Q58EX7-2	(1110)

PTHR10328:SF3

0.0748

0.0183

936.32

MANE_bad

HUMAN

sp|P61244

(160)

–>

sp|P61244-2

(151)

PTHR10383:SF16

0.0935

0.0102

932.87

MANE_good

HUMAN

sp|Q86VE9

(423)

–>

sp|Q86VE9-4

(461)

PTHR10130:SF2

0.0680

0.0108

910.29

MANE_bad

HUMAN

sp|P50542

(639)

–>

sp|P50542-2

(602)

PTHR45840:SF4

0.1463

0.0005

870.95

MANE_good

HUMAN

sp|O75783

(438)

–>

sp|O75783-2

(373)

PTHR15715:SF22

0.0598

0.0031

864.88

MANE_bad

HUMAN

sp|Q14BN4

(828)

–>

sp|Q14BN4-2

(790)

PTHR45805:SF6

0.0221

0.0009

838.81

MANE_good

MOUSE	sp\|Q8R1B8	(470)	–>	sp\|Q8R1B8-1	(459)
HUMAN	sp\|Q92753	(470)	–>	sp\|Q92753-1	(459)

PTHR10848:SF0

0.1004

0.0099

820.87

MANE_bad

HUMAN

sp|Q9Y5K1

(396)

–>

sp|Q9Y5K1-2

(358)

PTHR12474:SF3

0.2074

0.0141

816.41

MANE_good

HUMAN

sp|Q9Y6P5

(492)

–>

sp|Q9Y6P5-2

(551)

PTHR24023:SF58

0.0613

0.0143

796.78

MANE_bad

HUMAN

sp|P02458

(1487)

–>

sp|P02458-1

(1418)

PTHR16156:SF9

0.0296

0.0000

790.00

MANE_bad

HUMAN

sp|Q6ULP2

(936)

–>

sp|Q6ULP2-6

(909)

PTHR15653:SF3

0.1000

0.0118

788.08

MANE_bad

HUMAN

sp|Q13033

(797)

–>

sp|Q13033-2

(713)

PTHR10459:SF60

0.0454

0.0226

783.71

MANE_good

HUMAN

sp|Q9UGN5

(583)

–>

sp|Q9UGN5-2

(570)

PTHR11003:SF104

0.0367

0.0139

776.83

MANE_good

HUMAN

sp|Q96T55

(309)

–>

sp|Q96T55-3

(294)

PTHR15481:SF2

0.0747

0.0003

766.74

MANE_bad

HUMAN

sp|Q15287

(305)

–>

sp|Q15287-2

(282)

PTHR12999:SF21

0.0305

0.0003

764.08

MANE_bad

HUMAN

sp|O95218

(330)

–>

sp|O95218-2

(320)

PTHR24055:SF222

0.1082

0.0074

760.41

MANE_bad

HUMAN

sp|P45983

(427)

–>

sp|P45983-2

(384)

PTHR11328:SF29

0.0243

0.0005

759.92

MANE_good

HUMAN

sp|Q8NA29

(543)

–>

sp|Q8NA29-2

(530)

PTHR14196:SF4

0.1016

0.0005

758.94

MANE_bad

HUMAN

sp|Q8N2R0

(312)

–>

sp|Q8N2R0-2

(276)

PTHR12191:SF4

0.0531

0.0010

758.93

MANE_bad

HUMAN

sp|Q504Y0

(691)

–>

sp|Q504Y0-3

(654)

PTHR21139:SF24

0.1271

0.0008

756.07

MANE_bad

RABIT

sp|P00939

(249)

–>

sp|P00939-2

(288)

PTHR12394:SF11

0.0814

0.0081

755.85

MANE_bad

HUMAN

sp|Q9UHY8

(353)

–>

sp|Q9UHY8-2

(380)

PTHR10953:SF6

0.0297

0.0000

746.50

MANE_bad

HUMAN

sp|Q8TBC4

(463)

–>

sp|Q8TBC4-2

(449)

PTHR11636:SF84

0.1349

0.0180

739.88

MANE_bad

MOUSE

sp|Q00286

(291)

–>

sp|Q00286-3

(317)

PTHR43903:SF4

0.0306

0.0000

730.89

MANE_bad

HUMAN

sp|Q9NZ94

(848)

–>

sp|Q9NZ94-3

(808)

PTHR46251:SF1

0.1460

0.0036

726.46

MANE_bad

HUMAN

sp|Q96NL0

(473)

–>

sp|Q96NL0-4

(407)

PTHR10410:SF34

0.0993

0.0192

716.79

MANE_good

HUMAN

sp|P46736

(316)

–>

sp|P46736-2

(291)

PTHR46318:SF4

0.0579

0.0114

712.79

MANE_bad

HUMAN

sp|P17480

(764)

–>

sp|P17480-2

(727)

PTHR24343:SF345

0.0284

0.0010

710.93

MANE_good

HUMAN

sp|Q6SA08

(328)

–>

sp|Q6SA08-2

(338)

PTHR11461:SF129

0.0508

0.0162

705.95

MANE_good

HUMAN

sp|A8MV23

(424)

–>

sp|A8MV23-2

(404)

PTHR10012:SF0

0.0979

0.0002

696.94

MANE_good

HUMAN

sp|Q15257

(358)

–>

sp|Q15257-2

(323)

PTHR23103:SF7

0.0239

0.0006

688.77

MANE_bad

HUMAN

sp|P05067

(770)

–>

sp|P05067-9

(752)

PTHR45780:SF2

0.0591

0.0168

679.79

MANE_good

RAT

sp|O88637

(404)

–>

sp|O88637-2

(386)

PTHR11806:SF0

0.0350

0.0002

678.94

MANE_good

HUMAN

sp|Q9Y2Z2

(717)

–>

sp|Q9Y2Z2-4

(692)

PTHR10730:SF6

0.0273

0.0001

666.70

MANE_good

RAT

sp|Q811A3

(737)

–>

sp|Q811A3-2

(758)

PTHR48012:SF17

0.0232

0.0001

662.88

MANE_bad

HUMAN

sp|Q8IVH8

(894)

–>

sp|Q8IVH8-3

(873)

PTHR46845:SF1

0.2187

0.0246

651.53

MANE_good

HUMAN

sp|P05019

(195)

–>

sp|P05019-2

(153)

PTHR15081:SF1

0.4547

0.0113

633.99

MANE_bad

HUMAN

sp|P49321

(788)

–>

sp|P49321-2

(449)

PTHR31109:SF2

0.0865

0.0212

618.05

MANE_bad

HUMAN

sp|Q9NSI2

(230)

–>

sp|Q9NSI2-2

(215)

PTHR24543:SF333

0.0205

0.0000

610.87

MANE_bad

HUMAN

sp|O43854

(480)

–>

sp|O43854-2

(470)

PTHR10372:SF6

0.0332

0.0000

608.31

MANE_bad

HUMAN

sp|O60716

(968)

–>

sp|O60716-3

(939)

PTHR24372:SF71

0.0264

0.0002

604.81

MANE_bad

HUMAN

sp|O75473

(907)

–>

sp|O75473-2

(883)

PTHR28309:SF1

0.1105

0.0036

572.27

MANE_bad

HUMAN

sp|Q96EN9

(201)

–>

sp|Q96EN9-3

(179)

PTHR11731:SF109

0.0331

0.0013

572.22

MANE_good

HUMAN

sp|Q86TI2

(863)

–>

sp|Q86TI2-2

(892)

PTHR21844:SF2

0.0731

0.0025

558.50

MANE_bad

HUMAN

sp|Q96B36

(256)

–>

sp|Q96B36-3

(276)

PTHR12327:SF0

0.1986

0.0056

556.88

MANE_bad

HUMAN

sp|Q5SQI0

(421)

–>

sp|Q5SQI0-4

(333)

PTHR23176:SF103

0.0254

0.0001

545.93

MANE_good

HUMAN

sp|Q9BRR9

(750)

–>

sp|Q9BRR9-2

(731)

PTHR46333:SF3

0.0464

0.0183

536.78

MANE_bad

HUMAN

sp|Q8NBH2

(661)

–>

sp|Q8NBH2-3

(640)

PTHR11267:SF91

0.0430

0.0166

535.93

MANE_good

HUMAN

sp|O15119

(743)

–>

sp|O15119-2

(723)

PTHR24377:SF218

0.0293

0.0008

523.99

MANE_good

HUMAN

sp|P17025

(639)

–>

sp|P17025-2

(620)

PTHR24381:SF27

0.0642

0.0233

521.99

MANE_good

HUMAN

sp|Q9UJW8

(692)

–>

sp|Q9UJW8-2

(665)

PTHR24056:SF154

0.0822

0.0001

516.91

MANE_bad

HUMAN

sp|O94921

(469)

–>

sp|O94921-3

(423)

PTHR11616:SF263

0.1726

0.0082

514.35

MANE_good

MOUSE

sp|P28571

(692)

–>

sp|P28571-1

(633)

PTHR14789:SF2

0.0208

0.0001

512.92

MANE_good

HUMAN

sp|Q6UX15

(382)

–>

sp|Q6UX15-2

(374)

PTHR45993:SF4

0.0987

0.0201

509.90

MANE_bad

HUMAN

sp|Q9C0K0

(894)

–>

sp|Q9C0K0-2

(823)

PTHR10269:SF2

0.1140

0.0155

496.80

MANE_good

HUMAN

sp|Q9GZZ7

(299)

–>

sp|Q9GZZ7-2

(269)

PTHR16515:SF32

0.0601

0.0123

486.82

MANE_bad

HUMAN

sp|Q9NQX1

(630)

–>

sp|Q9NQX1-2

(599)

PTHR11544:SF14

0.2031

0.0177

466.28

MANE_bad

HUMAN

sp|P16989

(372)

–>

sp|P16989-2

(303)

PTHR24356:SF300

0.4022

0.0022

463.86

MANE_bad

MOUSE

sp|Q9WVC6

(431)

–>

sp|Q9WVC6-2

(524)

PTHR17615:SF8

0.3517

0.0184

449.46

MANE_good

HUMAN

sp|Q15884

(450)

–>

sp|Q15884-4

(603)

PTHR46054:SF2

0.1448

0.0006

424.73

MANE_bad

HUMAN

sp|O95793

(577)

–>

sp|O95793-3

(502)

PTHR13681:SF24

0.1205

0.0001

400.17

MANE_good

HUMAN

sp|Q9H7E2

(651)

–>

sp|Q9H7E2-3

(744)

PTHR24278:SF26

0.0464

0.0024

399.97

MANE_good

HUMAN

sp|P08709

(466)

–>

sp|P08709-2

(444)

PTHR46145:SF3

0.1515

0.0116

396.81

MANE_bad

HUMAN

sp|Q9Y251

(543)

–>

sp|Q9Y251-3

(469)

PTHR16262:SF2

0.1758

0.0167

386.13

MANE_bad

HUMAN

sp|Q7Z412

(305)

–>

sp|Q7Z412-2

(256)

PTHR12302:SF3

0.0353

0.0129

376.16

MANE_bad

HUMAN

sp|Q9BXU1

(1019)

–>

sp|Q9BXU1-3

(996)

PTHR46731:SF1

0.1383

0.0160

374.64

MANE_bad

HUMAN

sp|Q8NCQ5

(510)

–>

sp|Q8NCQ5-2

(434)

PTHR11036:SF11

0.0324

0.0008

372.25

MANE_bad

HUMAN

sp|Q9H3T2

(930)

–>

sp|Q9H3T2-3

(962)

PTHR46022:SF5

0.0447

0.0019

354.05

MANE_bad

HUMAN

sp|Q13635

(1447)

–>

sp|Q13635-3

(1381)

PTHR11100:SF7

0.1499

0.0078

351.16

MANE_good

RAT

sp|P43322

(662)

–>

sp|P43322-2

(639)

PTHR15919:SF12

0.0567

0.0126

315.77

MANE_good

HUMAN

sp|Q9NYF0

(836)

–>

sp|Q9NYF0-2

(799)

PTHR11738:SF186

0.1011

0.0185

310.08

MANE_bad

HUMAN

sp|Q8IYS5

(282)

–>

sp|Q8IYS5-2

(263)

PTHR11347:SF85

0.0908

0.0089

306.80

MANE_bad

HUMAN

sp|O60658

(829)

–>

sp|O60658-6

(757)

PTHR24092:SF98

0.0375

0.0062

292.78

MANE_bad

HUMAN

sp|Q9NTI2

(1188)

–>

sp|Q9NTI2-1

(1148)

PTHR12867:SF7

0.9093

0.0012

266.84

MANE_bad

HUMAN

sp|Q9NP73

(1137)

–>

sp|Q9NP73-2

(165)

PTHR16207:SF1

0.1337

0.0070

265.46

MANE_bad

HUMAN

sp|Q9UK61

(1670)

–>

sp|Q9UK61-4

(1609)

PTHR12745:SF4

0.1322

0.0198

260.55

MANE_bad

HUMAN

sp|Q8TDW4

(575)

–>

sp|Q8TDW4-2

(544)

PTHR32000:SF3

0.2206

0.0142

256.10

MANE_bad

HUMAN

sp|Q49A92

(538)

–>

sp|Q49A92-2

(427)

PTHR10044:SF163

0.0768

0.0180

245.70

MANE_bad

HUMAN

sp|Q96CA5

(298)

–>

sp|Q96CA5-2

(280)

PTHR24343:SF540

0.4103

0.0015

231.55

MANE_bad

HUMAN

sp|O14757

(476)

–>

sp|O14757-3

(442)

PTHR24377:SF610

0.0951

0.0001

226.82

MANE_good

HUMAN

sp|Q68DY9

(489)

–>

sp|Q68DY9-3

(448)

PTHR11929:SF132

0.2049

0.0097

217.65

MANE_bad

HUMAN

sp|P22083

(530)

–>

sp|P22083-2

(405)

PTHR24388:SF51

0.0940

0.0100

216.10

MANE_bad

HUMAN

sp|Q9Y2X9

(895)

–>

sp|Q9Y2X9-2

(859)

PTHR13943:SF2

0.0487

0.0145

210.02

MANE_good

HUMAN

sp|Q96KN8

(279)

–>

sp|Q96KN8-3

(269)

PTHR31997:SF2

0.4028

0.0012

206.80

MANE_bad

HUMAN

sp|A5PLN7

(773)

–>

sp|A5PLN7-2

(482)

PTHR13924:SF11

0.6471

0.0101

206.72

MANE_bad

HUMAN

sp|O95359

(2948)

–>

sp|O95359-5

(1094)

PTHR12322:SF117

0.3506

0.0084

200.55

MANE_bad

HUMAN

sp|Q5HYR2

(192)

–>

sp|Q5HYR2-2

(127)

PTHR22035:SF4

0.5231

0.0018

186.14

MANE_bad

HUMAN

sp|Q96M83

(1385)

–>

sp|Q96M83-3

(486)

PTHR14002:SF9

0.0925

0.0165

185.70

MANE_bad

HUMAN

sp|H3BV60

(292)

–>

sp|H3BV60-2

(316)

PTHR24390:SF124

0.1423

0.0015

174.09

MANE_good

HUMAN

sp|Q8IZ20

(524)

–>

sp|Q8IZ20-2

(504)

PTHR24028:SF117

0.1477

0.0174

146.59

MANE_bad

HUMAN

sp|Q9UN71

(923)

–>

sp|Q9UN71-2

(803)

PTHR21642:SF4

0.0991

0.0017

143.63

MANE_bad

HUMAN

sp|Q9BSQ5

(444)

–>

sp|Q9BSQ5-2

(465)

PTHR11690:SF132

0.2098

0.0194

142.53

MANE_bad

HUMAN

sp|P51172

(802)

–>

sp|P51172-1

(638)

PTHR24345:SF43

0.1382

0.0018

126.67

MANE_bad

HUMAN

sp|Q496M5

(336)

–>

sp|Q496M5-2

(299)

PTHR21402:SF3

0.2215

0.0075

126.62

MANE_bad

HUMAN

sp|Q9H1H1

(148)

–>

sp|Q9H1H1-2

(123)

PTHR10129:SF9

0.0856

0.0097

125.97

MANE_good

HUMAN

sp|O75444

(373)

–>

sp|O75444-1

(403)

PTHR24349:SF63

0.0817

0.0014

116.64

MANE_bad

HUMAN

sp|P49137

(400)

–>

sp|P49137-2

(370)

PTHR24406:SF36

0.0775

0.0149

115.67

MANE_bad

HUMAN

sp|Q8NI51

(663)

–>

sp|Q8NI51-7

(700)

PTHR10125:SF12

0.1241

0.0156

96.46

MANE_good

HUMAN

sp|Q93086

(444)

–>

sp|Q93086-3

(422)

PTHR34347:SF1

0.1353

0.0160

96.45

MANE_bad

HUMAN

sp|Q14159

(915)

–>

sp|Q14159-2

(845)

PTHR36881:SF1

0.1946

0.0014

95.94

MANE_bad

HUMAN

sp|Q6E0U4

(476)

–>

sp|Q6E0U4-2

(466)

PTHR24381:SF386

0.1813

0.0037

86.50

MANE_good

HUMAN

sp|Q96BR6

(464)

–>

sp|Q96BR6-2

(378)

PTHR23411:SF30

0.2332

0.0098

86.06

HUMAN

sp|P01854

(546)

–>

sp|P01854-1

(428)

PTHR10125:SF4

0.0691

0.0030

85.87

MANE_bad

HUMAN

sp|Q9UBL9

(471)

–>

sp|Q9UBL9-4

(497)

PTHR12035:SF127

0.2296

0.0020

75.46

MANE_bad

HUMAN

sp|Q96RL6

(698)

–>

sp|Q96RL6-2

(602)

PTHR24103:SF702

0.1085

0.0100

66.31

MANE_bad

HUMAN

sp|O75679

(317)

–>

sp|O75679-2

(288)

PTHR16165:SF3

0.2556

0.0085

56.21

MANE_bad

HUMAN

sp|Q8N323

(547)

–>

sp|Q8N323-2

(405)

PTHR10078:SF24

0.3031

0.0004

55.64

MANE_good

HUMAN

sp|Q9NZH7

(164)

–>

sp|Q9NZH7-2

(157)

PTHR14199:SF29

0.0560

0.0079

55.21

MANE_bad

HUMAN

sp|Q5VWK0

(638)

–>

sp|Q5VWK0-2

(667)

PTHR11949:SF10

0.0915

0.0075

45.19

MANE_good

HUMAN

sp|Q13568

(498)

–>

sp|Q13568-2

(514)

PTHR24100:SF151

0.0380

0.0112

45.06

MANE_bad

HUMAN

sp|O75144

(302)

–>

sp|O75144-2

(309)

PTHR38493:SF1

0.3174

0.0127

45.01

MANE_bad

HUMAN

sp|Q5SNV9

(1449)

–>

sp|Q5SNV9-3

(1468)